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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 15.15
Human Site: S51 Identified Species: 25.64
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S51 E V S K K P A S G P G A V V R
Chimpanzee Pan troglodytes XP_528522 404 44489 S51 E V S K K P A S G P G A V V R
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S51 E V S K K P G S G P G V V V R
Dog Lupus familis XP_548392 428 46939 G49 A S E G A G G G R R V V A G R
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 A55 K K F R K S K A L A G S G V P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 S60 G G E K Q K G S H K V D V V R
Chicken Gallus gallus XP_001236410 416 45873 S49 T S N E P L P S A Q T N T K K
Frog Xenopus laevis Q91560 421 46679 T49 I T T K T G E T K K V S L L L
Zebra Danio Brachydanio rerio XP_002665913 418 47625 C66 T D G Q D Y S C N W R K L L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 S51 E T S K E D K S N I T S K A L
Poplar Tree Populus trichocarpa XP_002300407 274 31114
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 K50 S S E T L K R K A E E S Q Q Q
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 86.6 6.6 N.A. 20 N.A. N.A. 33.3 6.6 6.6 0 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 100 86.6 6.6 N.A. 46.6 N.A. N.A. 40 26.6 40 33.3 N.A. N.A. 0 N.A. 40
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 0 N.A. N.A. N.A. 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 15 8 15 8 0 15 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 8 0 0 0 0 0 8 0 0 0 % D
% Glu: 29 0 22 8 8 0 8 0 0 8 8 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 8 8 0 15 22 8 22 0 29 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 8 0 43 29 15 15 8 8 15 0 8 8 8 8 % K
% Leu: 0 0 0 0 8 8 0 0 8 0 0 0 15 15 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 15 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 8 22 8 0 0 22 0 0 0 0 8 % P
% Gln: 0 0 0 8 8 0 0 0 0 8 0 0 8 8 15 % Q
% Arg: 0 0 0 8 0 0 8 0 8 8 8 0 0 0 36 % R
% Ser: 8 22 29 0 0 8 8 43 0 0 0 29 0 0 0 % S
% Thr: 15 15 8 8 8 0 0 8 0 0 15 0 8 0 0 % T
% Val: 0 22 0 0 0 0 0 0 0 0 22 15 29 36 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _